Exeter Pride has confirmed that there would be no Pride march, festival or marketplace this year.
The Northernhay and Rougemont Gardens event has attracted up to 15,000 people in recent years.
Simon Bowkett, co-chair of Exeter Pride said: “We have been following government and health advice closely and we cannot justify risking any compromise to the health of our community.
“We are sorry if this disappoints people who were looking forward to our usual get-togethers but look out for what we have in-store in the near and distant future.”